Initiators are a set of numbers which can generate a sequence. This appendix provides simple cubic and quadratic polynomials for calculating the initiator sequences associated with 1st and higher order maximal independent sets. Based on the constant g defined for the hypergeometric equation, sequence values can be readily calculated for odd values of g where g = 3 represents Perrin numbers. The repeated pattern of a(n) = n for small odd n is common to these sequences and suggests a pattern in nature which leads to diversity and variation of structure. An example of a DNA sequence calculated from a higher order MIS sequence is shown (see above) to produce this variation in structure.